Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,918 questions · 5,537 findings · 1,803 reviews

No studies found 1,309 · 23.6%GRADE not reported 440 · 7.9%Very low 1,560 · 28.2%Low 1,292 · 23.3%Moderate 751 · 13.6%High 185 · 3.3%

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Cediranib plus chemotherapy vs placebo plus chemotherapy

Serious adverse events · women with persistent, recurrent, or metastatic cervical cancer

Cediranib plus chemotherapy showed no clear difference in serious adverse events compared with placebo plus chemotherapy (low certainty).

1 finding from 1 review

Posterior reconstruction vs no posterior reconstruction

Serious adverse events · men (ages > 18 years) with clinically localized prostate cancer

Posterior reconstruction showed no clear difference in serious adverse events compared with no posterior reconstruction (moderate certainty).

1 finding from 1 review