Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,918 questions · 5,537 findings · 1,803 reviews

No studies found 1,309 · 23.6%GRADE not reported 440 · 7.9%Very low 1,560 · 28.2%Low 1,292 · 23.3%Moderate 751 · 13.6%High 185 · 3.3%

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Zinc vs placebo

Adverse events · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)

It is very uncertain whether zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… changes adverse events compared with placebo (very low certainty).

1 finding from 1 review

Acupuncture vs sham control

Adverse events · Patients with idiopathic dysgeusia and hypogeusia

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative infraorbital nerve block vs Intravenous analgesia

Adverse events · Children up to 13 years of age, undergoing cleft lip repair surgery
1 finding from 1 review

Preoperative ibuprofen vs placebo

Adverse events · Children and adolescents having orthodontic separator placement (without local anaesthetic)
1 finding from 1 review

Intervention not reported

Adverse events · acute treatment of migraine in adolescents

The intervention probably leads to higher adverse events (moderate certainty).

1 finding from 1 review