Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

15 questions · 15 findings · 4 reviews · Vascular

No studies found 6 · 40%GRADE not reported 0 · 0%Very low 3 · 20%Low 5 · 33.3%Moderate 1 · 6.7%High 0 · 0%

Balneotherapy vs no treatment

Adverse events: thromboembolic events · people with chronic venous insufficiency

Balneotherapy showed no clear difference in adverse effects of treatment (thromboembolic event) compared with no treatment (low certainty).

1 finding from 1 review

TNF‐α blockers intervention vs placebo or additional treatment

Adverse effects after treatment initiation: infections · children diagnosed with Kawasaki disease

TNF‐α blockers intervention showed no clear difference in adverse effects after treatment initiation: infections compared with placebo or additional treatment (low certainty).

1 finding from 1 review

IVIg vs different infusion regimens of IVIG

Incidence of any adverse effects after treatment initiation ( · people undergoing initial treatment for KD

Primary treatment with intravenous immunoglobulin (IVIG) showed no clear difference in incidence of any adverse effects after treatment initiation ( compared with different infusion regimens of IVIG (low certainty).

1 finding from 1 review

TNF‐α blockers intervention vs placebo or additional treatment

Rash · children diagnosed with Kawasaki disease

It is very uncertain whether TNF‐α blockers intervention changes adverse effects after treatment initiation: cutaneous reactions (rash) compared with placebo or additional treatment (very low certainty).

1 finding from 1 review

IVIg vs prednisolone

Incidence of any adverse effects after treatment initiation ( · people undergoing initial treatment for KD

Primary treatment with intravenous immunoglobulin (IVIG) showed no clear difference in incidence of any adverse effects after treatment initiation (up to 3… compared with prednisolone (low certainty).

1 finding from 1 review

TNF‐α blockers intervention vs placebo or additional treatment

Adverse effects: contact dermatitis · children diagnosed with Kawasaki disease

It is very uncertain whether TNF‐α blockers intervention changes adverse effects after treatment initiation: cutaneous reactions… compared with placebo or additional treatment (very low certainty).

1 finding from 1 review

IVIg vs acetylsalicylic acid (ASA)

Incidence of any adverse effects after treatment initiation ( · people undergoing initial treatment for KD

It is very uncertain whether primary treatment with intravenous immunoglobulin (IVIG) changes incidence of any adverse effects after treatment initiation (from 30… compared with acetylsalicylic acid (ASA) (very low certainty).

1 finding from 1 review

TNF‐α blockers intervention vs placebo or additional treatment

Adverse effects after treatment initiation: injection site reactions, neutropenia, infections, demyelinating disease, heart failure, malignancy, and induction of autoimmunity. · children diagnosed with Kawasaki disease

The review found no eligible studies for this question.

1 finding from 1 review