Findings

What do systematic reviews say?

1,949 questions · 1,994 findings · 636 reviews

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No studies found 504 · 25.3%GRADE not reported 340 · 17.1%Very low 477 · 23.9%Low 390 · 19.6%Moderate 241 · 12.1%High 42 · 2.1%

Comparison #1: Decision coaching vs usual care ‐ Summary of findings

Decision regret

1 finding from 1 review

Decision coaching for people making healthcare decisions 2021 · Cochrane Headline outcomes only
2019
2 studies · 170 participants
Very low

SCS treatment for 7 or fewer days vs SCS treatment

Adverse drug effects Gastrointestinal tract bleeding, symptomatic gastrointestinal reflux, symptoms of congestive heart failure or ischaemic heart disease, sleep disturbance, fractures, depression · exacerbations of COPD

SCS treatment for 7 or fewer days showed no clear difference in adverse drug effects Gastrointestinal tract bleeding, symptomatic… compared with SCS treatment (low certainty).

1 finding from 1 review

Different durations of corticosteroid therapy for exacerbations of chronic obstructive pulmonary disease 2018 · Cochrane Headline outcomes only
OR 0.88 [0.46, 1.7]
5 studies · 503 participants
Low

Inactivated influenza vaccine vs placebo

Asthma exacerbation (adverse effects) caused by inactivated influenza vaccine, measured in the first 2 weeks following vaccination ‐ children (over 3 years of age) given inactivated influenza vaccine · people with asthma

1 finding from 1 review

Vaccines for preventing influenza in people with asthma 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 712 participants
Moderate

Summary of findings table 1: comparison of operation types: early results of needle fasciotomy vs limited fasciectomy

Paraesthesia · 125 hands in 121 participants with Dupuytren's disease of the fingers for early outcomes (van Rijssen 2006)

1 finding from 1 review

Surgery for Dupuytren's contracture of the fingers 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 117 participants
Low

Comparison #3: Decision coaching plus evidence‐based information vs evidence‐based information ‐ Summary of findings

Anxiety (adverse effect, post‐intervention)

1 finding from 1 review

Decision coaching for people making healthcare decisions 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 340 participants
Very low

Clobazam vs phenytoin

Retention [ · drug‐naïve people with focal or generalized seizures with solitary cysticercus granuloma

Clobazam may leads to higher retention at 6 months (measured by the number of treatment failures… compared with phenytoin (low certainty).

1 finding from 1 review

Clobazam monotherapy for focal or generalized seizures 2018 · Cochrane Headline outcomes only
RR 1.43 [1.08, 1.9]
1 study · 48 participants
Low

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Adverse effects (insufficient fixation; re-operation/revision; plate exposure; superficial or deep wound infection; sinus tract; wound dehiscence; giant cell/foreign body or inflammatory reaction; post-traumatic dystrophy) · Adults over 18 years of age with fractures of the facial skeleton including the mandible, maxilla, zygoma (malar); studies on fractures of…

The review found no eligible studies for this question.

1 finding from 1 review

Resorbable versus titanium plates for facial fractures 2009 · Cochrane All outcomes
Up to 3 years postoperatively
Planned adverse-effects outcome not assessed: none of the retrieved studies met the inclusion criteria, so no data were available for analysis. Verbatim (Effects of interventions): "Although 53 studies were retrieved…
0 studies
No studies found

Application of heat vs application of cold

Adverse events due to treatment Minor adverse events, reported in studies as: exacerbation in pain after treatment; burn as a result of hot‐water immersion, or transient erythema, or adverse effects due to application of ice · people stung accidentally by bluebottle jellyfish (Physalia) and box jellyfish that do not cause Irukandji syndrome (Hawaiian box…

It is very uncertain whether application of heat changes adverse events due to treatment Minor adverse events, reported in… compared with application of cold (very low certainty).

1 finding from 1 review

Interventions for the symptoms and signs resulting from jellyfish stings 2023 · Cochrane Headline outcomes only
RR 0.5 [0.05, 5.19]
2 studies · 142 participants
Very low

Vitrectomy vs scleral buckling

Adverse effects (cataract development, choroidal detachment, new/iatrogenic breaks, postoperative proliferative vitreoretinopathy, postoperative increase in intraocular pressure, development of cystoid macular oedema, macular pucker, strabismus) a... · people with simple rhegmatogenous retinal detachments

Pars plana vitrectomy (PPV) may leads to higher adverse effects (cataract development, choroidal detachment,… compared with scleral buckling (low certainty).

1 finding from 1 review

Pars plana vitrectomy versus scleral buckling for repairing simple rhegmatogenous retinal detachments 2019 · Cochrane Headline outcomes only
OR 1.71
1 participants
Low