Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

77 questions · 77 findings · 10 reviews · Eyes and Vision

No studies found 27 · 35.1%GRADE not reported 2 · 2.6%Very low 7 · 9.1%Low 31 · 40.3%Moderate 9 · 11.7%High 1 · 1.3%

Surgery vs botulinum neurotoxin injections

Treatment success: improvement in the angle of strabismus at 6 months · children with infantile esotropia

It is very uncertain whether surgery changes treatment success: improvement in the angle of strabismus at 6 months compared with botulinum neurotoxin injections (very low certainty).

1 finding from 1 review

Surgery vs no surgery

Proportion of eyes with gain in VA by 0.3 logMAR or greater · people with epiretinal membrane

It is very uncertain whether surgery changes proportion of eyes with gain in VA by 0.3 logMAR or greater compared with no surgery (very low certainty).

1 finding from 1 review

Surgery vs no surgery

Proportion of eyes with loss in VA by 0.3 logMAR or greater · people with epiretinal membrane

Surgery may leads to lower proportion of eyes with loss in VA by 0.3 logMAR or greater compared with no surgery (low certainty).

1 finding from 1 review

Combined surgery vs phacoemulsification alone

Mean change in medications Measured by number of bottles · patients with eyes with cataract and glaucoma

Combined surgery showed no clear difference in mean change in medications Measured by number of bottles compared with phacoemulsification alone (low certainty).

1 finding from 1 review

Combined surgery vs phacoemulsification alone

Proportion using one or more medications at one year after surgery Number of participants · patients with eyes with cataract and glaucoma

Combined surgery may leads to lower proportion using one or more medications at one year after surgery… compared with phacoemulsification alone (low certainty).

1 finding from 1 review

Combined surgery vs phacoemulsification alone

Need for additional surgery: proportion of participants who received additional surgery to control IOP at 1 year · patients with eyes with cataract and glaucoma

Combined surgery showed no clear difference in proportion who received re‐operation to control IOP within one year… compared with phacoemulsification alone (low certainty).

1 finding from 1 review

Combined surgery vs phacoemulsification alone

Proportion who received intervention for surgical complications within one year Number of participants · patients with eyes with cataract and glaucoma

Combined surgery showed no clear difference in proportion who received intervention for surgical complications… compared with phacoemulsification alone (low certainty).

1 finding from 1 review

Immediate cataract surgery vs delayed cataract surgery

Development of choroidal neovascularization · people with cataract and age‐related macular degeneration

It is very uncertain whether immediate cataract surgery changes development of choroidal neovascularization compared with delayed cataract surgery (very low certainty).

1 finding from 1 review