Healing of osteonecrosis - healed ('healed' vs 'improved', 'unchanged' or 'worse') · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
Hyperbaric oxygen therapy plus standard care (surgery, antibiotics,… showed no clear difference in healing of osteonecrosis - healed ('healed' vs 'improved',… compared with standard care alone (surgery, antibiotics, oral rinse); GRADE not reported.
5 findings from 1 review
RR 1.56 [0.77, 3.18]
1 study · 46 participants
GRADE not reported
RR 1.00 [0.25, 4.00]
1 study · 18 participants
GRADE not reported
RR 0.95 [0.44, 2.04]
1 study · 40 participants
GRADE not reported
Show 2 more findings
Pain · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
1 finding from 1 review
Adverse effects · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Quality of life · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
1 finding from 1 review
Overall survival, induction cisplatin + 5-fluorouracil + docetaxel prior to concurrent chemoradiation (cisplatin) vs concurrent chemoradiation (cisplatin) · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Induction chemotherapy plus locoregional treatment (radiotherapy… showed no clear difference in overall survival, induction cisplatin + 5-fluorouracil + docetaxel… compared with locoregional treatment (radiotherapy and/or surgery) alone (low certainty).
1 finding from 1 review
Locoregional control · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Induction chemotherapy plus locoregional treatment (radiotherapy… led to lower locoregional control, induction cisplatin + 5-fluorouracil +… compared with locoregional treatment (radiotherapy and/or surgery) alone; GRADE not reported.
1 finding from 1 review
RR 0.80 [0.64, 0.99]
3 studies
GRADE not reported
Overall survival, induction platinum + 5-fluorouracil prior to surgery vs surgery alone · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Induction chemotherapy plus locoregional treatment (radiotherapy… showed no clear difference in overall survival, induction platinum + 5-fluorouracil prior to… compared with locoregional treatment (radiotherapy and/or surgery) alone (low certainty).
1 finding from 1 review
Overall survival, induction platinum + 5-fluorouracil prior to radiotherapy vs radiotherapy alone · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Induction chemotherapy plus locoregional treatment (radiotherapy… showed no clear difference in overall survival, induction platinum + 5-fluorouracil prior to… compared with locoregional treatment (radiotherapy and/or surgery) alone (moderate certainty).
1 finding from 1 review
Disease-free survival · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Induction chemotherapy plus locoregional treatment (radiotherapy… led to lower disease-free survival, induction platinum + 5-fluorouracil prior to… compared with locoregional treatment (radiotherapy and/or surgery) alone; GRADE not reported.
1 finding from 1 review
Overall survival, induction cisplatin + 5-fluorouracil prior to concurrent chemoradiation (cisplatin) vs concurrent chemoradiation (cisplatin) · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Induction chemotherapy plus locoregional treatment (radiotherapy… showed no clear difference in overall survival, induction cisplatin + 5-fluorouracil prior to… compared with locoregional treatment (radiotherapy and/or surgery) alone (low certainty).
1 finding from 1 review
Change in QoL SNOT‐20 · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
1 finding from 1 review
Complications of surgery · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
1 finding from 1 review
FEV1 % predicted: absolute change from baseline · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
1 finding from 1 review
Eradication of bacterial infection · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
1 finding from 1 review
Clinical improvement(visual analogue scale) · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
1 finding from 1 review
Pulmonary exacerbations · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
1 finding from 1 review
All‐cause mortality · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Gingival index (GI) · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age
Periodontal treatment (subgingival instrumentation, with or without… led to lower gingival index (GI) compared with no active intervention/usual care; GRADE not reported.
1 finding from 1 review
SMD -1.75 [-2.27, -1.24]
12 studies
GRADE not reported
HbA1c (glycated haemoglobin), change · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age
Periodontal treatment (subgingival instrumentation, with or without… probably leads to lower hbA1c (glycated haemoglobin), change compared with no active intervention/usual care (moderate certainty).
1 finding from 1 review
Quality of life indicators · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age
1 finding from 1 review