Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

557 questions · 600 findings · 75 reviews

No studies found 188 · 31.3%GRADE not reported 62 · 10.3%Very low 154 · 25.7%Low 122 · 20.3%Moderate 62 · 10.3%High 12 · 2%

Pelvic floor muscle training before and after prolapse surgery vs no training

Objective failure at any site: at 12 to 24 months · women undergoing pelvic organ prolapse surgery

Pelvic floor muscle training before and after prolapse surgery showed no clear difference in objective failure at any site: at 12 to 24 months compared with no training (moderate certainty).

1 finding from 1 review

Pelvic floor muscle training before and after prolapse surgery vs no training

Repeat surgery (or pessary) for recurrent prolapse · women undergoing pelvic organ prolapse surgery

Pelvic floor muscle training before and after prolapse surgery showed no clear difference in repeat surgery (or pessary) for recurrent prolapse compared with no training (low certainty).

1 finding from 1 review

Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone

The proportion of pressure ulcers healed · people with venous leg ulcers

Subfascial endoscopic perforator vein surgery (SEPS) + compression may leads to higher proportion with ulcers healed at 24 months compared with compression alone (low certainty).

1 finding from 1 review

Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone

Recurrence of ulcers · people with venous leg ulcers

It is very uncertain whether subfascial endoscopic perforator vein surgery (SEPS) + compression changes ulcer recurrence at 24 months compared with compression alone (very low certainty).

1 finding from 1 review

Prophylactic plasma transfusion before surgery/invasive procedures vs no prophylactic plasma transfusion before surgery/invasive procedures (colloid, crystalloid, placebo, or no treatment)

All‐cause mortality up to 30 days № of participants: 72 (1 RCT) · patients undergoing non‐cardiac surgery/invasive procedures

It is very uncertain whether prophylactic plasma transfusion before surgery/invasive procedures changes all‐cause mortality up to 30 days № of participants: 72 (1 RCT) compared with no prophylactic plasma transfusion before surgery/invasive… (very low certainty).

1 finding from 1 review

Prophylactic plasma transfusion before surgery/invasive procedures vs alternative haemostatic agents

Number of transfusions per participant within 7 days ‐ not reported · patients undergoing non‐cardiac surgery/invasive procedures

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic plasma transfusion before surgery/invasive procedures vs alternative haemostatic agents

Serious adverse events measured by plasma transfusion‐related complications within 24 hours № of participants: 21 (1 RCT) · patients undergoing non‐cardiac surgery/invasive procedures

It is very uncertain whether prophylactic plasma transfusion before surgery/invasive procedures changes serious adverse events measured by plasma transfusion‐related… compared with alternative haemostatic agents (very low certainty).

1 finding from 1 review

Prophylactic plasma transfusion before surgery/invasive procedures vs alternative haemostatic agents

Serious adverse events measured by surgery or procedure‐related complications within 30 days ‐ not reported · patients undergoing non‐cardiac surgery/invasive procedures

The review found no eligible studies for this question.

1 finding from 1 review