Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

557 questions · 600 findings · 75 reviews

No studies found 188 · 31.3%GRADE not reported 62 · 10.3%Very low 154 · 25.7%Low 122 · 20.3%Moderate 62 · 10.3%High 12 · 2%

Surgery plus Heister jaw opener vs Surgery plus wooden tongue depressors

Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)

It is very uncertain whether surgery plus Heister jaw opener changes maximal mouth opening (interincisal distance) compared with surgery plus wooden tongue depressors (very low certainty).

2 findings from 1 review

Surgery plus Heister jaw opener vs Surgery plus wooden tongue depressors

Burning sensation (VAS 0-100) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
1 finding from 1 review
  • Vadepally 2019 measured burning sensation on a VAS but did not fully report results, stating there was no significant difference between the 2 groups (p=0.617).
    1 study · 50 participants
    GRADE not reported

Ultra‐radical (extensive) surgery vs surgery

Survival (overall and disease‐ specific) · women with stage IIIc or IV ovarian cancer

It is very uncertain whether ultra‐radical (extensive) surgery changes survival (overall and disease‐ specific) compared with standard surgery (very low certainty).

1 finding from 1 review

Ultra‐radical (extensive) surgery vs surgery

Progression‐free survival · women with stage IIIc or IV ovarian cancer

It is very uncertain whether ultra‐radical (extensive) surgery changes progression‐free survival compared with standard surgery (very low certainty).

1 finding from 1 review

Ultra‐radical (extensive) surgery vs surgery

Disease-free survival · women with stage IIIc or IV ovarian cancer

It is very uncertain whether ultra‐radical (extensive) surgery changes disease‐free survival compared with standard surgery (very low certainty).

1 finding from 1 review

Ultra‐radical (extensive) surgery vs surgery

Perioperative mortality · women with stage IIIc or IV ovarian cancer

It is very uncertain whether ultra‐radical (extensive) surgery changes adverse event: perioperative mortality compared with standard surgery (very low certainty).

1 finding from 1 review

Ultra‐radical (extensive) surgery vs surgery

Adverse event: serious postoperative morbidity · women with stage IIIc or IV ovarian cancer

It is very uncertain whether ultra‐radical (extensive) surgery changes adverse event: serious postoperative morbidity compared with standard surgery (very low certainty).

1 finding from 1 review