Tranquil or asleep: Not tranquil or asleep · people with psychosis‐induced aggression
HALOPERIDOL + PROMETHAZINE leads to higher tranquil or asleep: Not tranquil or asleep compared with BENZODIAZEPINES ‐ MIDAZOLAM (high certainty).
1 finding from 1 review
Global outcome ‐ need for restraint or seclusion · people with psychosis‐induced aggression
HALOPERIDOL + PROMETHAZINE showed no clear difference in global state: Needing restraints or seclusion‐ by 2 hours compared with BENZODIAZEPINES ‐ MIDAZOLAM (moderate certainty).
1 finding from 1 review
Adverse effect: Specific ‐ Death · people with psychosis‐induced aggression
1 finding from 1 review
Not discharged from hospital · people with psychosis‐induced aggression
HALOPERIDOL + PROMETHAZINE showed no clear difference in service outcomes: Not discharged ‐ compared with BENZODIAZEPINES ‐ MIDAZOLAM (high certainty).
1 finding from 1 review
Adverse effect: Specific ‐ Death · people with psychosis‐induced aggression
1 finding from 1 review
Specific behavioursAggression · people with psychosis‐induced aggression
1 finding from 1 review
no estimate extracted
4 participants
GRADE not reported
Economic outcomes: Cost of care · people with psychosis‐induced aggression
1 finding from 1 review
Service outcomes: Not discharged ‐ by 2 weeks · people with psychosis‐induced aggression
HALOPERIDOL + PROMETHAZINE showed no clear difference in service outcomes: Not discharged ‐ by 2 weeks compared with ANTIPSYCHOTIC ‐ HALOPERIDOL (high certainty).
1 finding from 1 review
Aggression · people with psychosis‐induced aggression
1 finding from 1 review
Economic outcomes: Cost of care · people with psychosis‐induced aggression
1 finding from 1 review
Tranquil or asleep: Not tranquil or asleep ‐ by 30 mins · people with psychosis‐induced aggression
HALOPERIDOL + PROMETHAZINE showed no clear difference in tranquil or asleep: Not tranquil or asleep ‐ by 30 mins compared with ANTIPSYCHOTIC ‐ OLANZAPINE (high certainty).
1 finding from 1 review
Global state: Needing restraints or seclusion ‐ by 12 hours · people with psychosis‐induced aggression
HALOPERIDOL + PROMETHAZINE showed no clear difference in global state: Needing restraints or seclusion by 12 hours compared with ANTIPSYCHOTIC ‐ OLANZAPINE (low certainty).
1 finding from 1 review
Global state: 2. Clinically important change (no improvement) ‐ long term · schizophrenia
It is very uncertain whether haloperidol discontinuation changes global state: clinically important change ‒ not improved (CGI) compared with haloperidol continuation (very low certainty).
1 finding from 1 review
Relapse · schizophrenia
It is very uncertain whether haloperidol discontinuation changes global state: relapse: ‒ compared with haloperidol continuation (very low certainty).
1 finding from 1 review
Mental state: clinically important change in mental state · schizophrenia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
General functioning: clinically important change in general functioning including working ability · schizophrenia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Behaviour: clinically important change in general behaviour · schizophrenia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life: clinically important change in quality of life · schizophrenia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Satisfaction with treatment: leaving the study early Endpoint data (events) · schizophrenia
It is very uncertain whether haloperidol discontinuation changes satisfaction with treatment: leaving the study early compared with haloperidol continuation (very low certainty).
1 finding from 1 review
Symptoms of delirium within 24 hoursa · terminally ill adults with delirium
Summary of findings: haloperidol showed no clear difference in symptoms of delirium within 24 hoursa compared with placebo (low certainty).
1 finding from 1 review