Question · asked by 1 review
Haloperidol discontinuation vs haloperidol continuation: Global state: 2. Clinically important change (no improvement) ‐ long term
- Population
- schizophrenia
- Intervention
- Haloperidol discontinuation
- Comparison
- haloperidol continuation
- Outcome
- Global state: 2. Clinically important change (no improvement) ‐ long term
It is very uncertain whether haloperidol discontinuation changes global state: clinically important change ‒ not improved (CGI) compared with haloperidol continuation (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Haloperidol discontinuation vs haloperidol continuation Global state: clinically important change ‒ not improved (CGI) · schizophrenia It is very uncertain whether haloperidol discontinuation changes global state: clinically important change ‒ not improved (CGI) compared with haloperidol continuation (very low certainty). Haloperidol discontinuation for people with schizophrenia (2019) · Cochrane Headline outcomes only | RR 2.06 [1.33, 3.2] | 1 study · 49 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Haloperidol discontinuation for people with schizophrenia 2019 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.