Findings

What do systematic reviews say?

186 questions · 195 findings · 13 reviews

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No studies found 63 · 32.3%GRADE not reported 3 · 1.5%Very low 46 · 23.6%Low 51 · 26.2%Moderate 17 · 8.7%High 15 · 7.7%

Manual therapy and exercise vs placebo

Function · rotator cuff disease

1 finding from 1 review

Manual therapy and exercise for rotator cuff disease 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 120 participants
High

Manual therapy and exercise vs placebo

Pain on motion · rotator cuff disease

1 finding from 1 review

Manual therapy and exercise for rotator cuff disease 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 120 participants
High

Manual therapy and exercise vs placebo

Global assessment of treatment success · rotator cuff disease

Manual therapy and exercise showed no clear difference in global assessment of treatment success compared with placebo (high certainty).

1 finding from 1 review

Manual therapy and exercise for rotator cuff disease 2016 · Cochrane Headline outcomes only
RR 1.39 [0.94, 2.03]
1 study · 112 participants
High

Manual therapy and exercise vs placebo

Quality of life · rotator cuff disease

1 finding from 1 review

Manual therapy and exercise for rotator cuff disease 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 120 participants
High

Manual therapy and exercise vs placebo

Adverse events · rotator cuff disease

Manual therapy and exercise leads to higher adverse events compared with placebo (high certainty).

1 finding from 1 review

Manual therapy and exercise for rotator cuff disease 2016 · Cochrane Headline outcomes only
RR 3.77 [1.49, 9.54]
1 study · 116 participants
High

Manual therapy and exercise vs glucocorticoid injection

Overall pain · rotator cuff disease

1 finding from 1 review

Manual therapy and exercise for rotator cuff disease 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 88 participants
Low

Manual therapy and exercise vs glucocorticoid injection

Function · rotator cuff disease

1 finding from 1 review

Manual therapy and exercise for rotator cuff disease 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 88 participants
Low

Manual therapy and exercise vs glucocorticoid injection

Pain on motion · rotator cuff disease

The review found no eligible studies for this question.

1 finding from 1 review

Manual therapy and exercise for rotator cuff disease 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise therapy plus antidepressants vs antidepressants alone

FatigueMeasured at end of treatment, 26 weeks · men and women aged over 18 years with chronic fatigue syndrome

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Very low

Exercise therapy plus antidepressants vs antidepressants alone

Fatigue · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise therapy plus antidepressants vs antidepressants alone

Participants with serious adverse reactions · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise therapy plus antidepressants vs antidepressants alone

Pain End of treatment and long term · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise therapy plus antidepressants vs antidepressants alone

Physical functioning End of treatment and long term · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise therapy plus antidepressants vs antidepressants alone

QoL · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise therapy plus antidepressants vs antidepressants alone

Depression Measured after 52 weeks HADS depression score, 0‐21 points Low score means fewer symptoms · men and women aged over 18 years with chronic fatigue syndrome

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 44 participants
Very low

Exercise therapy plus antidepressants vs antidepressants alone

Depression Long term · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise therapy plus antidepressants vs antidepressants alone

Sleep · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Manual therapy and exercise vs glucocorticoid injection

Participant‐reported pain relief of 30% or greater · patients with adhesive capsulitis (frozen shoulder)

The review found no eligible studies for this question.

1 finding from 1 review

Manual therapy and exercise for adhesive capsulitis (frozen shoulder) 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Manual therapy and exercise vs glucocorticoid injection

Overall pain (change from baseline) · patients with adhesive capsulitis (frozen shoulder)

1 finding from 1 review

Manual therapy and exercise for adhesive capsulitis (frozen shoulder) 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 107 participants
Moderate

Manual therapy and exercise vs glucocorticoid injection

Function (change from baseline) Shoulder Disabilty Questionnaire 0‐100 (lower scores = better function) · patients with adhesive capsulitis (frozen shoulder)

1 finding from 1 review

Manual therapy and exercise for adhesive capsulitis (frozen shoulder) 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 107 participants
Moderate