Corticosteroids vs placebo or no treatment
- Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedHigh
Neonatal and child outcomes: corticosteroids probably leads to lower developmental delay in childhood№ of participants: 600 (3 RCTs). Age… compared with placebo or no treatment (moderate certainty).
It is very uncertain whether summary of findings: inhaled corticosteroids changes respiratory exacerbations: number of days on intravenous antibiotics… compared with placebo (very low certainty).
It is very uncertain whether standard treatment plus systemic corticosteroids changes length of hospital stay compared with standard treatment alone (very low certainty).
It is very uncertain whether standard treatment plus systemic corticosteroids changes preservation of visual acuity compared with standard treatment alone (very low certainty).
It is very uncertain whether standard treatment plus systemic corticosteroids changes severity of pain on day 3 compared with standard treatment alone (very low certainty).
It is very uncertain whether standard treatment plus systemic corticosteroids changes duration of time requiring intravenous antibiotics compared with standard treatment alone (very low certainty).
It is very uncertain whether standard treatment plus systemic corticosteroids changes need for surgical intervention compared with standard treatment alone (very low certainty).
It is very uncertain whether standard treatment plus systemic corticosteroids changes adverse effects: exposure keratopathy compared with standard treatment alone (very low certainty).
The review found no eligible studies for this question.
Effect of antenatal corticosteroids (betamethasone) showed no clear difference in respiratory distress syndrome (RDS) compared with usual care prior to planned caesarean at term on maternal and… (low certainty).
Effect of antenatal corticosteroids (betamethasone) showed no clear difference in transient tachypnoea of the neonate (TTN) compared with usual care prior to planned caesarean at term on maternal and… (low certainty).
Effect of antenatal corticosteroids (betamethasone) probably leads to lower admission to neonatal special care (all levels) for respiratory… compared with usual care prior to planned caesarean at term on maternal and… (moderate certainty).
It is very uncertain whether effect of antenatal corticosteroids (betamethasone) changes need for mechanical ventilation compared with usual care prior to planned caesarean at term on maternal and… (very low certainty).