Question · asked by 1 review

Brimonidine vs apraclonidine: IOP increase of ≥ 5 mmHg within 2 hours

It is very uncertain whether brimonidine changes IOP increase of ≥ 5 mmHg within 2 hours compared with apraclonidine (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Brimonidine vs apraclonidine
IOP increase of ≥ 5 mmHg within 2 hours · people with glaucoma receiving LTP
It is very uncertain whether brimonidine changes IOP increase of ≥ 5 mmHg within 2 hours compared with apraclonidine (very low certainty).
Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane Headline outcomes only
RR 2.28 [0.32, 16.03]2 studies · 71 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.