Question · asked by 1 review

CCBs vs diuretics: Congestive heart failure

Population
patients with hypertension
Intervention
CCBs
Comparison
diuretics
Outcome
Congestive heart failure

CCBs probably leads to higher congestive heart failure compared with diuretic (moderate certainty).

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 100%High 0 · 0%
FindingEffectStudiesGRADE certainty
CCBs vs diuretic
Congestive heart failure · patients with hypertension
CCBs probably leads to higher congestive heart failure compared with diuretic (moderate certainty).
Calcium channel blockers versus other classes of drugs for hypertension (2022) · Cochrane Headline outcomes only
RR 1.37 [1.25, 1.51]5 studies · 34072 participantsModerate
CCBs vs diuretic
Congestive heart failure · patients with hypertension
CCBs probably leads to higher congestive heart failure compared with diuretic (moderate certainty).
Calcium channel blockers versus other classes of drugs for hypertension (2021) · Cochrane Headline outcomes onlyearlier version CD003654.PUB5, superseded
RR 1.37 [1.25, 1.51]5 studies · 34072 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Calcium channel blockers versus other classes of drugs for hypertension
2022 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.