Question · asked by 1 review

Transdermal or intranasal nicotine vs placebo: Hourly morphine equivalents at 60 minutes

Transdermal or intranasal nicotine showed no clear difference in hourly morphine equivalents at 60 minutes compared with placebo (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Transdermal or intranasal nicotine vs placebo
Hourly morphine equivalents at 60 minutes · people being treated for postoperative pain
Transdermal or intranasal nicotine showed no clear difference in hourly morphine equivalents at 60 minutes compared with placebo (low certainty).
Intranasal or transdermal nicotine for the treatment of postoperative pain (2016) · Cochrane Headline outcomes only
no estimate extracted4 studies · 168 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Intranasal or transdermal nicotine for the treatment of postoperative pain
2016 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.