Question · asked by 1 review

Elective neck dissection (at time of primary tumour resection) vs Therapeutic (delayed) neck dissection: Recurrence

Population
Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes
Intervention
Elective neck dissection (at time of primary tumour resection)
Comparison
Therapeutic (delayed) neck dissection
Outcome
Recurrence

Elective neck dissection (at time of primary tumour resection) probably leads to lower recurrence compared with therapeutic (delayed) neck dissection (moderate certainty).

What each review found

Current versions only
No studies found 1 · 33.3%GRADE not reported 1 · 33.3%Very low 0 · 0%Low 0 · 0%Moderate 1 · 33.3%High 0 · 0%
FindingEffectStudiesGRADE certainty
Elective neck dissection (at time of primary tumour resection) vs Therapeutic (delayed) neck dissection
Recurrence · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes · 3 years
Elective neck dissection (at time of primary tumour resection) probably leads to lower recurrence compared with therapeutic (delayed) neck dissection (moderate certainty).
Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment (2023) · Cochrane All outcomes
RR 0.58 [0.48, 0.70]3 studies · 633 participantsModerate
Elective neck dissection (at time of primary tumour resection) vs Therapeutic (delayed) neck dissection
Recurrence · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes
The review found no eligible studies for this question.
Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment (2018) · Cochrane All outcomesearlier version CD006205.PUB4, superseded
Recurrence: no data presented (0 participants, 0 studies).0 studiesNo studies found
Elective neck dissection (at time of primary tumour resection) vs Therapeutic (delayed) neck dissection
Recurrence · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes
Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment (2011) · Cochrane All outcomesearlier version CD006205.PUB3, superseded
Two trials reported recurrence at different sites (Vandenbrouck 1980; Yuen 2009); numbers too small to determine a difference.2 studiesGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment
2023 · Cochrane All outcomes
2022-02Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.