Mannitol vs phenolphthalein or rhubarb soda: Global or clinical change in constipation as defined by the study a) Still constipated (no defecation) at 24 hours
It is very uncertain whether mannitol changes global or clinical change in constipation as defined by the study a)… compared with phenolphthalein or rhubarb soda (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Mannitol vs phenolphthalein or rhubarb soda Global or clinical change in constipation as defined by the study a) Still constipated (no defecation) at 24 hours · antipsychotic‐related constipation It is very uncertain whether mannitol changes global or clinical change in constipation as defined by the study a)… compared with phenolphthalein or rhubarb soda (very low certainty). Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane Headline outcomes only | RR 0.07 [0.02, 0.27] | 1 study · 240 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pharmacological treatment for antipsychotic‐related constipation 2017 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.