Triclosan/copolymer-containing fluoride toothpaste vs Fluoride toothpaste without triclosan: Tooth staining/discolouration (adverse effect)
- Population
- Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in practice mostly adults, with children in 2 studies
- Intervention
- Triclosan/copolymer-containing fluoride toothpaste
- Comparison
- Fluoride toothpaste without triclosan
- Outcome
- Tooth staining/discolouration (adverse effect)
Triclosan/copolymer-containing fluoride toothpaste showed no clear difference in adverse effects (tooth staining, Meckel Stain Score, 6 months) compared with fluoride toothpaste without triclosan; GRADE not reported.
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Triclosan/copolymer-containing fluoride toothpaste vs Fluoride toothpaste without triclosan Adverse effects (tooth staining, Meckel Stain Score, 6 months) · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in… · 6 months Triclosan/copolymer-containing fluoride toothpaste showed no clear difference in adverse effects (tooth staining, Meckel Stain Score, 6 months) compared with fluoride toothpaste without triclosan; GRADE not reported. Triclosan/copolymer containing toothpastes for oral health (2013) · Cochrane All outcomes | MD -0.15 [-0.60, 0.30] | 1 study · 325 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Triclosan/copolymer containing toothpastes for oral health 2013 · Cochrane All outcomes | 2013-08 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.