Steroid therapy in first episode of nephrotic syndrome: 3 months or more vs two months: Number with frequent relapses by 12 to 24 months stratified by risk of bias for allocation concealment: unclear or high risk of bias for allocation bias
Steroid therapy in first episode of nephrotic syndrome: three months… probably leads to lower number with frequent relapses by 12 to 24 months stratified by risk… compared with two months (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Steroid therapy in first episode of nephrotic syndrome: three months of more vs two months Number with frequent relapses by 12 to 24 months stratified by risk of bias for allocation concealment: unclear or high risk of bias for allocation bias · patients with nephrotic syndrome in children Steroid therapy in first episode of nephrotic syndrome: three months… probably leads to lower number with frequent relapses by 12 to 24 months stratified by risk… compared with two months (moderate certainty). Corticosteroid therapy for nephrotic syndrome in children (2015) · Cochrane Headline outcomes onlyearlier version CD001533.PUB5, superseded | RR 0.45 [0.26, 0.77] | 3 studies · 220 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Corticosteroid therapy for nephrotic syndrome in children 2020 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.