Question · asked by 1 review

Vitamin D deficiency (serum 25(OH)D < 50 nmol/L) vs Serum 25(OH)D ≥ 75 nmol/l: Early childhood caries (ECC)

Population
Children aged 6 years or younger (preschool children)
Intervention
Vitamin D deficiency (serum 25(OH)D < 50 nmol/L)
Comparison
Serum 25(OH)D ≥ 75 nmol/l
Outcome
Early childhood caries (ECC)

Serum 25(OH)D <50 nmol/l (vs ≥75 nmol/l) was associated with higher odds of ECC (OR 2.00; ungraded).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Serum 25(OH)D < 50 nmol/l vs Serum 25(OH)D ≥ 75 nmol/l
Early childhood caries (ECC) · Preschool children ≤6 years
Serum 25(OH)D <50 nmol/l (vs ≥75 nmol/l) was associated with higher odds of ECC (OR 2.00; ungraded).
The Association Between Vitamin D and Early Childhood Caries: A Systematic Review and Meta-Analysis. (2024) All outcomes
OR 2.00 [1.76, 2.28]6 studies · 4807 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
The Association Between Vitamin D and Early Childhood Caries: A Systematic Review and Meta-Analysis.
2024 All outcomes
December 2021 to February 202212Not applicable

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.