Question · asked by 1 review

ORT‐based algorithm vs standard dose of FSH: Live birth or ongoing pregnancy

ORT‐based algorithm showed no clear difference in live birth or ongoing pregnancy compared with standard starting dose of FSH (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
ORT‐based algorithm vs standard starting dose of FSH
Live birth or ongoing pregnancy · women undergoing IVF/ICSI
ORT‐based algorithm showed no clear difference in live birth or ongoing pregnancy compared with standard starting dose of FSH (low certainty).
Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro… (2024) · Cochrane Headline outcomes only
OR 1.12 [0.98, 1.29]7 studies · 4400 participantsLow
ORT‐based algorithm vs standard dose of FSH
Live birth or ongoing pregnancy · women undergoing IVF/ICSI
ORT‐based algorithm showed no clear difference in live birth or ongoing pregnancy compared with standard dose of FSH (moderate certainty).
Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro… (2018) · Cochrane Headline outcomes onlyearlier version CD012693.PUB2, superseded
OR 1.04 [0.88, 1.23]4 studies · 2823 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro fertilisation plus…
2024 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.