Nalbuphine vs pethidine: Number of patients with the need for rescue analgesia (12 hours postoperatively)
- Population
- children undergoing surgery
- Intervention
- Nalbuphine
- Comparison
- pethidine
- Outcome
- Number of patients with the need for rescue analgesia (12 hours postoperatively)
Nalbuphine showed no clear difference in number of patients with the need for rescue analgesia (2 hours… compared with pethidine (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Nalbuphine vs pethidine Number of patients with the need for rescue analgesia (2 hours postoperatively) · children undergoing surgery Nalbuphine showed no clear difference in number of patients with the need for rescue analgesia (2 hours… compared with pethidine (low certainty). Nalbuphine for postoperative pain treatment in children (2014) · Cochrane Headline outcomes only | RR 1.07 [0.52, 2.23] | 1 study · 77 participants | Low |
Nalbuphine vs pethidine Number of patients with the need for rescue analgesia (24 hours postoperatively) · children undergoing surgery It is very uncertain whether nalbuphine changes number of patients with the need for rescue analgesia (24 hours… compared with pethidine (very low certainty). Nalbuphine for postoperative pain treatment in children (2014) · Cochrane Headline outcomes only | RR 1.13 [0.52, 2.44] | 1 study · 50 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Nalbuphine for postoperative pain treatment in children 2014 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
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How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.