Question · asked by 1 review

Summary of Findings Table ‐ PBI?APBI vs WBRT: Late radiotherapy toxicity (subcutaneous fibrosis)

Summary of Findings Table ‐ PBI?APBI probably leads to higher subcutaneous fibrosis (late RT toxicity) compared with WBRT (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Summary of Findings Table ‐ PBI?APBI vs WBRT
Subcutaneous fibrosis (late RT toxicity) · health problem or population
Summary of Findings Table ‐ PBI?APBI probably leads to higher subcutaneous fibrosis (late RT toxicity) compared with WBRT (moderate certainty).
Partial breast irradiation versus whole breast radiotherapy for early breast cancer (2021) · Cochrane Headline outcomes only
OR 5.07 [3.81, 6.74]2 studies · 3011 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Partial breast irradiation versus whole breast radiotherapy for early breast cancer
2021 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.