Question · asked by 1 review

Summary of findings: cycled vs culture‐based antibiotic therapy: Emergence of novel bacteria: isolation of novel gram negative organisms

Summary of findings: cycled showed no clear difference in emergence of novel bacteria: isolation of novel gram negative… compared with culture‐based antibiotic therapy (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Summary of findings: cycled vs culture‐based antibiotic therapy
Emergence of novel bacteria: isolation of novel gram negative organisms · children (aged 1 to 12 years) with CF and a newly isolated PA infection
Summary of findings: cycled showed no clear difference in emergence of novel bacteria: isolation of novel gram negative… compared with culture‐based antibiotic therapy (moderate certainty).
Treatments for preventing recurrence of infection with Pseudomonas aeruginosa in people with cystic fibrosis (2019) · Cochrane Headline outcomes only
RR 1 [0.67, 1.5]1 study · 253 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Treatments for preventing recurrence of infection with Pseudomonas aeruginosa in people with cystic fibrosis
2019 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.