Question · asked by 1 review

Helium vs carbon dioxide: Analgesia requirements

It is very uncertain whether helium changes analgesia requirements (morphine mg) compared with carbon dioxide (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Helium vs carbon dioxide
Analgesia requirements (morphine mg) · people undergoing laparoscopic general abdominal or gynaecological pelvic surgery under general anaesthesia
It is very uncertain whether helium changes analgesia requirements (morphine mg) compared with carbon dioxide (very low certainty).
Gases for establishing pneumoperitoneum during laparoscopic abdominal surgery (2022) · Cochrane Headline outcomes only
MD 12 [4.44, 19.56]1 study · 90 participantsVery low
Helium vs carbon dioxide
Analgesia requirements (morphine mg) · people undergoing laparoscopic general abdominal or gynaecological pelvic surgery under general anaesthesia
It is very uncertain whether helium changes analgesia requirements (morphine mg) compared with carbon dioxide (very low certainty).
Gases for establishing pneumoperitoneum during laparoscopic abdominal surgery (2017) · Cochrane Headline outcomes onlyearlier version CD009569.PUB3, superseded
MD 12 [4.44, 19.56]1 study · 90 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Gases for establishing pneumoperitoneum during laparoscopic abdominal surgery
2022 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.