Question · asked by 1 review

Higher BP target (< 150‐160/95‐105 mmHg) vs lower BP target (< 140/90 mmHg): Withdrawals due to adverse events

Population
older adults with primary hypertension
Intervention
Higher BP target (< 150‐160/95‐105 mmHg)
Comparison
lower BP target (< 140/90 mmHg)
Outcome
Withdrawals due to adverse events

Higher BP target (< 150‐160/95‐105 mmHg) showed no clear difference in withdrawals due to adverse effects compared with lower BP target (< 140/90 mmHg) (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Higher BP target (< 150‐160/95‐105 mmHg) vs lower BP target (< 140/90 mmHg)
Withdrawals due to adverse effects · older adults with primary hypertension
Higher BP target (< 150‐160/95‐105 mmHg) showed no clear difference in withdrawals due to adverse effects compared with lower BP target (< 140/90 mmHg) (low certainty).
Blood pressure targets for hypertension in older adults (2017) · Cochrane Headline outcomes only
RR 0.83 [0.58, 1.19]2 studies · 7497 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Blood pressure targets for hypertension in older adults
2017 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.