Question · asked by 1 review
Opioids vs no treatment/placebo: Pain (PIPP)
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Opioids vs no treatment/placebo Pain, assessed using the PIPP/PIPP‐R pain scale, ranging from 0 to 21 and 0 to 18 in preterm infants < 28 weeks' gestational age and full‐term infants, respectively, during procedure · neonates exposed to procedural pain Opioids for procedural pain in neonates (2023) · Cochrane Headline outcomes onlyearlier version CD015056.PUB2, superseded | no estimate extracted | 3 studies · 199 participants | Moderate |
Opioids vs no treatment/placebo Pain, assessed using the PIPP/PIPP‐R pain scale up to 30 min after procedure · neonates exposed to procedural pain Opioids for procedural pain in neonates (2023) · Cochrane Headline outcomes onlyearlier version CD015056.PUB2, superseded | no estimate extracted | 2 studies · 123 participants | Very low |
Opioids vs no treatment/placebo Pain, assessed using the PIPP/PIPP‐R pain scale 1 to 2 hours after procedure · neonates exposed to procedural pain Opioids for procedural pain in neonates (2023) · Cochrane Headline outcomes onlyearlier version CD015056.PUB2, superseded | no estimate extracted | 2 studies · 54 participants | Very low |
Opioids vs no treatment/placebo Pain, assessed using the PIPP/PIPP‐R pain scale, ranging from 0 to 21 and 0 to 18 in preterm infants < 28 weeks' gestational age and full‐term infants, respectively, during procedure · neonates exposed to procedural pain Opioids for procedural pain in neonates (2023) · Cochrane Headline outcomes only | no estimate extracted | 3 studies · 199 participants | Moderate |
Opioids vs no treatment/placebo Pain, assessed using the PIPP/PIPP‐R pain scale up to 30 min after procedure · neonates exposed to procedural pain Opioids for procedural pain in neonates (2023) · Cochrane Headline outcomes only | no estimate extracted | 2 studies · 123 participants | Very low |
Opioids vs no treatment/placebo Pain, assessed using the PIPP/PIPP‐R pain scale 1 to 2 hours after procedure · neonates exposed to procedural pain Opioids for procedural pain in neonates (2023) · Cochrane Headline outcomes only | no estimate extracted | 2 studies · 54 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Opioids for procedural pain in neonates 2023 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.