Question · asked by 1 review

Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery: Surgical recurrence (

It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes surgical recurrence ( compared with initiation of prophylactic therapy immediately after surgery (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery
Surgical recurrence ( · Adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease.
It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes surgical recurrence ( compared with initiation of prophylactic therapy immediately after surgery (very low certainty).
Colonoscopy‐guided therapy for the prevention of post‐operative recurrence of Crohn’s disease (2020) · Cochrane Headline outcomes only
RR 0.79 [0.38, 1.62]133 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Colonoscopy‐guided therapy for the prevention of post‐operative recurrence of Crohn’s disease
2020 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.