Vitamin D plus calcium vs placebo or no intervention: Preterm birth
- Population
- pregnant women and their infants..
- Intervention
- Vitamin D plus calcium
- Comparison
- placebo or no intervention
- Outcome
- Preterm birth
Vitamin D + calcium supplementation may leads to higher preterm birth (less than 37 weeks' gestation) compared with placebo or no intervention (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Vitamin D + calcium supplementation vs placebo or no intervention Preterm birth (less than 37 weeks' gestation) · pregnant women and their infants.. Vitamin D + calcium supplementation may leads to higher preterm birth (less than 37 weeks' gestation) compared with placebo or no intervention (low certainty). Vitamin D supplementation for women during pregnancy (2019) · Cochrane Headline outcomes only | RR 1.52 [1.01, 2.28] | 5 studies · 942 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Vitamin D supplementation for women during pregnancy 2019 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Vitamin D plus calcium vs no treatment/placebo (no vitamin or minerals) · pregnant women · 0 reviews
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.