GERD/NERD vs Healthy individuals without reflux (controls): Oral mucosa inflammation (gingivitis, periodontitis, mucosal lesions)
The association between reflux and oral mucosa inflammation (gingivitis/periodontitis) is inconsistent across five studies and remains ungraded.
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
GERD/NERD vs Healthy individuals without reflux (controls) Oral mucosa inflammation (gingivitis, periodontitis, mucosal lesions) · Adults with gastroesophageal reflux disease (GERD) or laryngopharyngeal reflux (LPR) · Adult patients in gastroenterology, ENT and dental clinical settings The association between reflux and oral mucosa inflammation (gingivitis/periodontitis) is inconsistent across five studies and remains ungraded. Laryngopharyngeal reflux, gastroesophageal reflux and dental disorders: A systematic review. (2020) All outcomes | Five studies examined gingival/periodontal and mucosal disorders with inconsistent results: some reported more frequent mucosal inflammatory findings in GERD patients (Yoshikawa, Watanabe, Vinesh 25.5% periodontitis,… | 5 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Laryngopharyngeal reflux, gastroesophageal reflux and dental disorders: A systematic review. 2020 All outcomes | January 1990 to December 2019 (publication period searched) | 24 | Not applicable |
Studies behind the findings
The primary studies the full-text reviews tie to this outcome. Reviews with headline outcomes only do not list them here.
- Risk factors associated with oral manifestations and oral health impact of gastro-oesophageal reflux disease: a multicentre,… · 2019 · included by 1 of these review
- A Clinicopathologic Study of Oral Changes in Gastroesophageal Reflux Disease, Gastritis, and Ulcerative Colitis · 2016 · included by 1 of these review
- Erosive esophageal reflux vs. non erosive esophageal reflux: oral findings in 71 patients. · 2015 · included by 1 of these review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.