Question · asked by 1 review
CHOLINERGIC DRUGS vs placebo: Adverse effects: Any adverse events
- Population
- patients with antipsychotic‐induced tardive dyskinesia
- Intervention
- CHOLINERGIC DRUGS
- Comparison
- placebo
- Outcome
- Adverse effects: Any adverse events
It is very uncertain whether CHOLINERGIC DRUGS changes adverse effects: Any adverse events compared with PLACEBO (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
CHOLINERGIC DRUGS vs PLACEBO Adverse effects: Any adverse events · people with various psychiatric disorders (mainly schizophrenia) and antipsychotic‐induced tardive dyskinesia It is very uncertain whether CHOLINERGIC DRUGS changes adverse effects: Any adverse events compared with PLACEBO (very low certainty). Cholinergic medication for antipsychotic‐induced tardive dyskinesia (2018) · Cochrane Headline outcomes only | RR 0.56 [0.15, 2.14] | 4 studies · 106 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Cholinergic medication for antipsychotic‐induced tardive dyskinesia 2018 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.