Question · asked by 1 review
Combinations of antipsychotic drugs vs single antipsychotic drugs: Leaving the study early
- Population
- schizophrenia or related disorders
- Intervention
- Combinations of antipsychotic drugs
- Comparison
- single antipsychotic drugs
- Outcome
- Leaving the study early
Combinations of antipsychotic drugs showed no clear difference in leaving the study early compared with single antipsychotic drugs (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Combinations of antipsychotic drugs vs single antipsychotic drugs Leaving the study early · schizophrenia or related disorders Combinations of antipsychotic drugs showed no clear difference in leaving the study early compared with single antipsychotic drugs (low certainty). Antipsychotic combinations for schizophrenia (2017) · Cochrane Headline outcomes only | RR 0.9 [0.76, 1.07] | 43 studies · 3137 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Antipsychotic combinations for schizophrenia 2017 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.