Antiretroviral therapy (any, including cART) vs No antiretroviral medication (treatment-naive): Parotid hypertrophy prevalence
Parotid hypertrophy was significantly more prevalent in treatment-naive CLWH than in those on ART (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Antiretroviral therapy (any, including cART) vs No antiretroviral medication (treatment-naive) Parotid hypertrophy prevalence · Children and adolescents (<18 years) living with HIV (CLWH) · Hospitals and AIDS outpatient centres in India, Brazil, and several Asian countries Parotid hypertrophy was significantly more prevalent in treatment-naive CLWH than in those on ART (very low certainty). Impact of Antiretroviral Therapy on Oral Health among Children Living with HIV: A Systematic Review and… (2022) All outcomes | OR 0.01 [0.00, 0.05] | Not reported | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Impact of Antiretroviral Therapy on Oral Health among Children Living with HIV: A Systematic Review and Meta-Analysis. 2022 All outcomes | 2022-08-03 (inception to 3 August 2022) | 14 | Critically Low / Low |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.