Question · asked by 1 review

Ciclesonide vs budesonide (dose ratio 1:2): Exacerbations

It is very uncertain whether ciclesonide changes patients with exacerbations Number of patients with exacerbations compared with budesonide (dose ratio 1:2) (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Ciclesonide vs budesonide (dose ratio 1:2)
Patients with exacerbations Number of patients with exacerbations · patients with chronic asthma in children
It is very uncertain whether ciclesonide changes patients with exacerbations Number of patients with exacerbations compared with budesonide (dose ratio 1:2) (very low certainty).
Ciclesonide versus other inhaled corticosteroids for chronic asthma in children (2013) · Cochrane Headline outcomes only
RR 2.2 [0.75, 6.43]2 studies · 1024 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Ciclesonide versus other inhaled corticosteroids for chronic asthma in children
2013 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.