Question · asked by 1 review

Combination vs single‐agent chemotherapy: Time to progression

Combination probably leads to lower time to progression compared with single‐agent chemotherapy (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Combination vs single‐agent chemotherapy
Time to progression · people with advanced gastric cancer
Combination probably leads to lower time to progression compared with single‐agent chemotherapy (moderate certainty).
Chemotherapy for advanced gastric cancer (2017) · Cochrane Headline outcomes only
HR 0.69 [0.55, 0.87]4 studies · 720 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Chemotherapy for advanced gastric cancer
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.