Question · asked by 1 review
Lower blood pressure targets vs standard blood pressure targets: Withdrawals due to adverse events
- Population
- cardiovascular disease with high blood pressure
- Intervention
- Lower blood pressure targets
- Comparison
- standard blood pressure targets
- Outcome
- Withdrawals due to adverse events
It is very uncertain whether lower blood pressure targets changes participant withdrawals due to adverse effects compared with standard blood pressure targets (very low certainty).
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 0 · 0%Very low 4 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Lower blood pressure targets vs standard blood pressure targets Participant withdrawals due to adverse effects · cardiovascular disease with high blood pressure It is very uncertain whether lower blood pressure targets changes participant withdrawals due to adverse effects compared with standard blood pressure targets (very low certainty). Blood pressure targets for the treatment of people with hypertension and cardiovascular disease (2022) · Cochrane Headline outcomes only | RR 8.16 [2.06, 32.28] | 3 studies · 801 participants | Very low |
Lower blood pressure targets vs standard blood pressure targets Participant withdrawals due to adverse effects · cardiovascular disease with high blood pressure It is very uncertain whether lower blood pressure targets changes participant withdrawals due to adverse effects compared with standard blood pressure targets (very low certainty). Blood pressure targets for the treatment of people with hypertension and cardiovascular disease (2020) · Cochrane Headline outcomes onlyearlier version CD010315.PUB4, superseded | RR 8.16 [2.06, 32.28] | 2 studies · 690 participants | Very low |
Lower blood pressure targets vs standard blood pressure targets Withdrawals due to adverse effects · cardiovascular disease with high blood pressure It is very uncertain whether lower blood pressure targets changes withdrawals due to adverse effects compared with standard blood pressure targets (very low certainty). Blood pressure targets for the treatment of people with hypertension and cardiovascular disease (2018) · Cochrane Headline outcomes onlyearlier version CD010315.PUB3, superseded | RR 8.16 [2.06, 32.28] | 2 studies · 690 participants | Very low |
Lower blood pressure targets vs standard blood pressure targets Withdrawals due to adverse effects · Cardiovascular disease with high blood pressure It is very uncertain whether lower blood pressure targets changes withdrawals due to adverse effects compared with standard blood pressure targets (very low certainty). Blood pressure targets for the treatment of people with hypertension and cardiovascular disease (2017) · Cochrane Headline outcomes onlyearlier version CD010315.PUB2, superseded | RR 8.16 [2.06, 32.28] | 2 studies · 690 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Blood pressure targets for the treatment of people with hypertension and cardiovascular disease 2022 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.