Question · asked by 1 review

Respiratory syncytial virus vaccine vs placebo: Preterm birth

Population
pregnant women
Intervention
Respiratory syncytial virus vaccine
Comparison
placebo
Outcome
Preterm birth

It is very uncertain whether respiratory syncytial virus vaccine changes preterm birth compared with placebo (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Respiratory syncytial virus vaccine vs placebo
Preterm birth · pregnant woman
It is very uncertain whether respiratory syncytial virus vaccine changes preterm birth compared with placebo (very low certainty).
Respiratory syncytial virus vaccination during pregnancy for improving infant outcomes (2024) · Cochrane Headline outcomes only
RR 1.16 [0.99, 1.36]6 studies · 17560 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Respiratory syncytial virus vaccination during pregnancy for improving infant outcomes
2024 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.