Question · asked by 1 review

Vortioxetine vs SNRIs: Total number of drop‐outs

It is very uncertain whether vortioxetine changes total number of drop‐outs compared with SNRIs (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Vortioxetine vs SNRIs
Total number of drop‐outs · adults with Major Depressive Disorder
It is very uncertain whether vortioxetine changes total number of drop‐outs compared with SNRIs (very low certainty).
Vortioxetine for depression in adults (2017) · Cochrane Headline outcomes only
RR 0.89 [0.73, 1.08]8 studies · 3159 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Vortioxetine for depression in adults
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.