Pharmacological interventions vs placebo: Acceptability
It is very uncertain whether pharmacological interventions changes acceptability ‐ drop‐outs due to any cause: post‐intervention compared with placebo (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Pharmacological interventions vs placebo acceptability ‐ drop‐outs due to any cause: post‐intervention · adults with long‐term physical conditions (18 years or older) It is very uncertain whether pharmacological interventions changes acceptability ‐ drop‐outs due to any cause: post‐intervention compared with placebo (very low certainty). Prevention of depression in adults with long‐term physical conditions (2021) · Cochrane Headline outcomes only | OR 1.13 [0.73, 1.73] | 9 studies · 962 participants | Very low |
Pharmacological interventions vs placebo acceptability ‐ drop‐outs due to any cause: 6‐12 months · adults with long‐term physical conditions (18 years or older) It is very uncertain whether pharmacological interventions changes acceptability ‐ drop‐outs due to any cause: 6‐12 months compared with placebo (very low certainty). Prevention of depression in adults with long‐term physical conditions (2021) · Cochrane Headline outcomes only | OR 1.13 [0.69, 1.86] | 3 studies · 327 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Prevention of depression in adults with long‐term physical conditions 2021 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.