Question · asked by 1 review
Surgery plus radiotherapy vs Chemotherapy (chemoradiotherapy): Total mortality
- Population
- Adults with oral cavity or oropharyngeal cancer
- Intervention
- Surgery plus radiotherapy
- Comparison
- Chemotherapy (chemoradiotherapy)
- Outcome
- Total mortality
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 1 · 50%Very low 1 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Surgery plus adjuvant radiotherapy vs Chemotherapy (chemoradiotherapy) Total mortality · Adults with oral cavity or oropharyngeal cancer · oral cavity Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment (2023) · Cochrane All outcomes | Total mortality: study reported survival significantly better with surgery and RT vs chemoradiotherapy, but no useable data; 32 participants (1 RCT, Iyer 2015 oral cavity subgroup). | 1 study · 32 participants | Very low |
Surgery plus adjuvant radiotherapy vs Chemotherapy (chemoradiotherapy) Total mortality · Adults with oral cavity or oropharyngeal cancer · oral cavity Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment (2018) · Cochrane All outcomesearlier version CD006205.PUB4, superseded | Total mortality (2 years): 'For the oral cavity, survival was significantly better in patients who underwent surgery and RT compared with the CRT group' (Iyer 2015); no useable data. No GRADE rating. | 1 study | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes | 2022-02 | Not listed | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Surgery plus radiotherapy vs Radiotherapy alone · Adults with oral cavity or oropharyngeal cancer · 1 review
- Surgery plus radiotherapy vs surgery · People with squamous cell carcinoma of the oral cavity or oropharynx · 0 reviews
- Surgery plus radiotherapy vs Radiotherapy alone · People with squamous cell carcinoma of the oral cavity or oropharynx · 0 reviews
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.