Genetically predicted DMFS (dental caries) vs Without dental caries (lower genetic liability): Lacunar stroke
Genetically predicted dental caries showed no significant causal association with lacunar stroke (ungraded MR).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Genetically predicted dental caries vs Without dental caries (lower genetic liability) Lacunar stroke · European-ancestry adults (GWAS) · Genetic epidemiology (European-ancestry GWAS summary data) Genetically predicted dental caries showed no significant causal association with lacunar stroke (ungraded MR). The contribution of oral infectious diseases in lacunar stroke based on meta-analysis and Mendelian… (2025) All outcomes | OR 0.92 [0.69, 1.23] | Not reported | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| The contribution of oral infectious diseases in lacunar stroke based on meta-analysis and Mendelian randomization study. 2025 All outcomes | August 2024 | 10 | Not applicable |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.