Question · asked by 1 review

Probiotics vs control: Mortality before hospital discharge

Probiotics probably leads to lower mortality (all‐cause before hospital discharge) compared with control (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Probiotics vs control
All‐cause mortality (before hospital discharge) · very preterm or very low birth weight infants
Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants (2023) · Cochrane Headline outcomes only
no estimate extracted54 studies · 10484 participantsModerate
Probiotics vs control
Mortality (all‐cause before hospital discharge) · very preterm or very low birth weight infants
Probiotics probably leads to lower mortality (all‐cause before hospital discharge) compared with control (moderate certainty).
Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants (2020) · Cochrane Headline outcomes onlyearlier version CD005496.PUB5, superseded
RR 0.76 [0.65, 0.89]51 studies · 10170 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants
2023 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.