Question · asked by 1 review
Any antihypertensive drug vs placebo or no treatment: Total mortality Mean duration of 3.8 years
- Population
- adults 60 years or older with primary hypertension
- Intervention
- Any antihypertensive drug
- Comparison
- placebo or no treatment
- Outcome
- Total mortality Mean duration of 3.8 years
Antihypertensive drug leads to lower total mortality Mean duration of 3.8 years compared with placebo or no treatment (high certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Antihypertensive drug vs placebo or no treatment Total mortality Mean duration of 3.8 years · adults 60 years or older with primary hypertension Antihypertensive drug leads to lower total mortality Mean duration of 3.8 years compared with placebo or no treatment (high certainty). Pharmacotherapy for hypertension in adults 60 years or older (2019) · Cochrane Headline outcomes only | RR 0.91 [0.85, 0.97] | 13 studies · 25932 participants | High |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pharmacotherapy for hypertension in adults 60 years or older 2019 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.