Question · asked by 1 review
Tranexamic acid vs placebo/no treatment: Serious maternal morbidity or death
- Population
- pregnant women undergoing vaginal or caesarean birth who received TA for the prevention of postpartum haemorrhage
- Intervention
- Tranexamic acid
- Comparison
- placebo/no treatment
- Outcome
- Serious maternal morbidity or death
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Tranexamic acid vs placebo/no treatment Maternal death or severe maternal morbidity such as seizure, thromboembolic events, need for intensive care unit admission, hysterectomy, organ failure · pregnant women undergoing vaginal or caesarean birth who received TA for the prevention of postpartum haemorrhage Tranexamic acid for preventing postpartum haemorrhage (2015) · Cochrane Headline outcomes only | no estimate extracted | 4 studies · 1511 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Tranexamic acid for preventing postpartum haemorrhage 2015 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.