Question · asked by 1 review

Intermittent 'as needed' ICS vs daily ICS: Change from baseline mean daily use of β2‐agonists (puffs/day) (duration 24 to 44 weeks)

Intermittent 'as needed' ICS showed no clear difference in change from baseline mean daily use of β2‐agonists (puffs/day)… compared with daily ICS (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Intermittent 'as needed' ICS vs daily ICS
Change from baseline mean daily use of β2‐agonists (puffs/day) (duration 24 to 44 weeks) · Children and adults with persistent asthma.
Intermittent 'as needed' ICS showed no clear difference in change from baseline mean daily use of β2‐agonists (puffs/day)… compared with daily ICS (moderate certainty).
Intermittent versus daily inhaled corticosteroids for persistent asthma in children and adults (2013) · Cochrane Headline outcomes only
MD 0.12 [0, 0.23]3 studies · 442 participantsModerate
Intermittent 'as needed' ICS vs daily ICS
Change from baseline mean daily use of β2‐agonists (puffs/day) (duration 24 to 44 weeks) · patients with persistent asthma in children and adults
Intermittent 'as needed' ICS showed no clear difference in change from baseline mean daily use of β2‐agonists (puffs/day)… compared with daily ICS (moderate certainty).
Intermittent versus daily inhaled corticosteroids for persistent asthma in children and adults (2012) · Cochrane Headline outcomes onlyearlier version CD009611.PUB2, superseded
MD 0.12 [0, 0.23]3 studies · 442 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Intermittent versus daily inhaled corticosteroids for persistent asthma in children and adults
2013 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.