Question · asked by 1 review
Ketamine/midazolam vs A different sedative agent: Behaviour
- Population
- Children and adolescents (0 to 16 years) needing dental treatment
- Intervention
- Ketamine/midazolam
- Comparison
- A different sedative agent
- Outcome
- Behaviour
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 2 · 66.7%Very low 1 · 33.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Ketamine/midazolam vs A different sedative agent Behaviour · Children and adolescents (0 to 16 years) needing dental treatment Sedation of children undergoing dental treatment (2018) · Cochrane All outcomes | Any behavioural score - Ketamine/midazolam versus (other sedatives): 27 (1); VERY LOW | 1 study · 27 participants | Very low |
Ketamine/midazolam vs A different sedative agent Behaviour · Children and adolescents (0 to 16 years) needing dental treatment Sedation of children undergoing dental treatment (2006) · Cochrane All outcomesearlier version CD003877.PUB3, superseded | Lokken 1994 and Roelofse 1996a: ketamine/midazolam combinations; no significant anxiety/pain differences. Narrative. | Not reported | GRADE not reported |
Ketamine/midazolam vs A different sedative agent Behaviour · Children and adolescents (0 to 16 years) needing dental treatment Sedation of children undergoing dental treatment (2005) · Cochrane All outcomesearlier version CD003877.PUB2, superseded | Lokken 1994 (midazolam vs midazolam/ketamine) no significant anxiety/pain difference; Roelofse 1996a (rectal ketamine/midazolam vs rectal midazolam) fewer adverse effects, reliably good sedation. Narrative. | Not reported | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Sedation of children undergoing dental treatment 2018 · Cochrane All outcomes | 22 February 2018 | Not listed | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Ketamine/midazolam vs placebo or no intervention · Children and adolescents (0 to 16 years) needing dental treatment · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.