Question · asked by 1 review
Ketamine/midazolam vs placebo or no intervention: Behaviour
- Population
- Children and adolescents (0 to 16 years) needing dental treatment
- Intervention
- Ketamine/midazolam
- Comparison
- placebo or no intervention
- Outcome
- Behaviour
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Midazolam/ketamine vs Placebo (including no intervention) Behaviour · Children and adolescents (0 to 16 years) needing dental treatment Sedation of children undergoing dental treatment (2018) · Cochrane All outcomes | Moreira 2013: 0.5 mg/kg midazolam + 3 mg/kg ketamine produced significantly better behaviour than placebo and oral midazolam (P=0.03); not included in meta-analysis / not GRADE-rated. Narrative. | 1 study | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Sedation of children undergoing dental treatment 2018 · Cochrane All outcomes | 22 February 2018 | Not listed | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Ketamine/midazolam vs A different sedative agent · Children and adolescents (0 to 16 years) needing dental treatment · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.