Summary of findings: Single vs combination intravenous anti‐pseudomonal antibiotic therapy: Change in sputum P aeruginosa density at end of treatment (cfu/g)
Summary of findings: single showed no clear difference in change in sputum P aeruginosa density at end of treatment (cfu/g) compared with combination intravenous anti‐pseudomonal antibiotic therapy (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Summary of findings: single vs combination intravenous anti‐pseudomonal antibiotic therapy Change in sputum P aeruginosa density at end of treatment (cfu/g) · children and adults with cystic fibrosis Summary of findings: single showed no clear difference in change in sputum P aeruginosa density at end of treatment (cfu/g) compared with combination intravenous anti‐pseudomonal antibiotic therapy (moderate certainty). Single versus combination intravenous anti‐pseudomonal antibiotic therapy for people with cystic fibrosis (2021) · Cochrane Headline outcomes only | no estimate extracted | 1 study · 76 participants | Moderate |
Summary of findings: Single vs combination intravenous anti‐pseudomonal antibiotic therapy Change in sputum P aeruginosa density at end of treatment (cfu/g) Â · children and adults with cystic fibrosis The review found no eligible studies for this question. Single versus combination intravenous anti‐pseudomonal antibiotic therapy for people with cystic fibrosis (2021) · Cochrane Headline outcomes only | no estimate extracted | Not reported | No studies found |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Single versus combination intravenous anti‐pseudomonal antibiotic therapy for people with cystic fibrosis 2021 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.