Question · asked by 1 review

GnRHa depot vs GnRHa daily injection: Miscarriage

GnRHa depot showed no clear difference in miscarriage rates compared with gnRHa daily injection (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
GnRHa depot vs GnRHa daily injection
Miscarriage rates · patients with pituitary down regulation in assisted reproduction cycles
GnRHa depot showed no clear difference in miscarriage rates compared with gnRHa daily injection (low certainty).
Depot versus daily administration of gonadotrophin‐releasing hormone agonist protocols for pituitary down… (2013) · Cochrane Headline outcomes only
OR 1.16 [0.7, 1.94]9 studies · 512 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Depot versus daily administration of gonadotrophin‐releasing hormone agonist protocols for pituitary down regulation in assisted…
2013 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.