Question · asked by 1 review

NSAIDs vs placebo: Withdrawals due to adverse events

Population
adults with fibromyalgia
Intervention
NSAIDs
Comparison
placebo
Outcome
Withdrawals due to adverse events

It is very uncertain whether NSAID changes adverse event withdrawal compared with placebo (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
NSAID vs placebo
Adverse event withdrawal · adults with fibromyalgia
It is very uncertain whether NSAID changes adverse event withdrawal compared with placebo (very low certainty).
Oral nonsteroidal anti‐inflammatory drugs for fibromyalgia in adults (2017) · Cochrane Headline outcomes only
RD 0.044 studies · 230 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Oral nonsteroidal anti‐inflammatory drugs for fibromyalgia in adults
2017 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.